


In the comics, the building was said to have been built upon the site of pagan sacrifices, and before that Native American rituals, and is a focal point for supernatural energies.

It is "in the heart of New York City's Greenwich Village." Contrary to fan theories that this address was meant to invoke 221B Baker Street, the fictional domicile of Sherlock Holmes, it was actually a reference to the address of an apartment shared in the 1960s by Roy Thomas and Gary Friedrich. The Sanctum Sanctorum is a three-story townhouse located at 177A Bleecker Street. Doctor Strange and Karl Mordo arrived just after the opnenig of the Dark Dimension, but Strange used the Eye of Agamotto and it's Time Stone to manipulate time to resurrect Wong and the other Masters of the Mystic Arts, to rebuild the Hong Kong Sanctum, and to save the Earth from Dormammu.177 Bleecker Street, New York City in 2013. Unfortunately, Kaecilius and his Zealots overpowered them and opened a portal to the Dark Dimension. The Masters of the Mystic Arts were forewarned and rallied to arms by Wong. After destroying the London Sanctum and the murder of the master of the New York Sanctum, the Zealots turned his attention to Hong Kong. To bring eternal life to the world, Kaecilius and his Zealots made a pact with Dormammu that necessitated the destruction of the three Sanctums. Master Tina Minoru acts as the current master and guardian of the Hong Kong Sanctum.

It had a fixed dimensional portal connecting it to Kamar-Taj in Nepal and a more conventional entrance on a busy street in the heart of Hong Kong. Along with the New York Sanctum and the London Sanctum, the Hong Kong Sanctum acted as a planet-wide mystical defensive ward and as a base from which the Masters of the Mystic Arts conducted their activities. The Hong Kong Sanctum is one of three Sanctums created by Agamotto and maintained by the Masters of the Mystic Arts.
